October 22, 2002

18.00-20.00 Registration

October 23, 2002

8.00 Registration

9.00 Welcome Addresses - L. Luzzatto (IST, Italy), A. Moccaldi (ISPELS, Italy), J. Henshaw (OSHA, USA), U. Verdel (INAIL, Italy), C. Perucci (ASL Roma E, Italy)

Introduction of the conference

9.30-10.00 01 Key note talk: Why are we still talking about silica, silicosis, and cancer? - G. Wagner

10.00-11.15 History of silica and silicosis - Chairs: F. Forastiere (Italy), L. Schuman (USA)

10.00-10.30 02 Key note talk: A long-lasting pandemic: diseases caused by dust containing silica in Italy in the international contest - F. Carnevale, A. Baldasseroni s17

10.30-10.45 03 After 20 years, crystalline silica dust is a carcinogen: scientific basis, clinical impacts, and future research - D.F. Goldsmith, T.L. Guidotti, U. Saffiotti s17

10.45-11.00 04 Successful silica control in the Vermont granite industry 1938-1960: political lessons learned and applied to silica control today - B. Rosenberg, C. Levenstein s18

11.00-11.15 05 Data base on exposure to respirable crystalline silica in Italian factories since ’60 to nowadays - P. Altarocca, P. La Pegna, F. Nappi, R. Piccioni, D. Rughi, G. Stefani, U. Verdel s18

11.15-11.45 Coffee break

11.45-13.15 Industrial Hygiene and ambient sampling methods - Chairs: F. Hurley (UK), D. Cottica (Italy)

11.45-12.15 06 Key note talk: The exposure metric: does a time-weighted calculation of working-lifetime exposure provide a better understanding of disease risk than the cumulative exposure? - N. Jin, C. Rice, M. Dosemeci, P.L. Cocco s18

12.15-12.30 07 Work environment and workers´ respiratory health in a small sand classification plant in Brazil - A.M.T. Bon, A.M.A. Santos, N. Kulcsar, N.C. Amaral, E. Algranti, M. Busico, R. Pizzol s19

12.30-12.45 08 Comparison of different methodologies of sampling crystalline silica for risk assessment in working environments - P. Santantonio, F. Cavariani, D. Cottica, R. Maldera, A. Marconi, A. Massola, U. Verdel, M. Casciani s19

12.45-13.00 09 Respirable dust and silica exposure of pottery workers in central Italy - G. Cattani, F. Cavariani, A. Marconi, A. Quercia s20

13.00-13.15 10 Brazilian job exposure matrix (JEM) for silica and strategies for surveillance - F.S. Ribeiro, V. Wünsch-Filho, E.A. Camargo s20

13.15-14.30 Lunch

14.30-15.30 Industrial hygiene and ambient sampling methods - Chairs: C. Rice (USA), G. Spagnoli (Italy)

14.30-14.45 11 Silver-coated capillary pore filters for crystalline silica analysis - R.J. Key-Schwartz, D.M. Ramsey s21

14-45-15.00 12 Surveillance and control of silica dust exposure during a high speed railway track in tunnel construction - I. Cenni, C. Cassinelli, P. Zoppi, A. Muller, M. Colucci, G. Fornaciai, S. Silvestri s21

15.00-15.15 13 Characterization of airborne particulates in the work environment of artistic and sanitary ceramic factories: final results - A. Massola, D. Cottica, G.C. Botta s22

15.15-15.30 14 Exposure to crystalline free silica in the artisan companies of artistic ceramics in Umbria (Central Italy) - M. Mecchia, F. Ruspolini s22

15.30-17.00 EXPERIMENTAL RESEARCH: ROLE OF PHYSICOCHEMICAL FEATURES - Chairs: U.F. Haustein (Germany), S. Palmi (Italy)

15.30-16.00 15 Key note talk: The chemical basis of the variability of crystalline silica hazard - B. Fubini s23

16.00-16.15 16 Reaction of ascorbic acid and thiols at the surface of crystalline silica: possible implications for a depletion of antioxidant defences in the lung lining layer - I. Fenoglio, S. Fonsato, M. Ghiazza, M. Tomatis, G. Martra, B. Fubini s23

16.15-16.30 17 Respirable silica particle occlusion by alumino-silicate: surface properties of dusts with disease risk anomalies - W.E. Wallace, J. Chen, J. Harrison, V. Hnizdo, W. Chen, J. Nelson, W. Chisholm, E. Hnizdo, M.J. Keane, W.E. Miller s24

16.30-16.45 18 Cytotoxic activity of yellow sand (Asian dust storm) with the reference to SiO2 and TiO2 - Y. Lim, K.A. Kim, H.S. Sohn, K.H. Lee s24

16.45-17.00 19 DNA damage by quartz in lung epithelial cells: in vitro and in vivo studies - R.P.F. Schins, A.M. Knaapen, C. Albrecht, A. Becker, G.D. Cakmak, D. Höhr, T. Shi, P.J.A. Borm s25

17.00-17.30 Coffee break

17.30-18.30 Autoimmune diseases - Chairs: P. Stratta (Italy), K. Steenland (USA)

17.30-17.45 20 Key note talk: Silica-induced scleroderma is not different from idiopathic disease - U.F. Haustein, U. Anderegg s25

17.45-18.00 21 ANCA positive vasculitis and silica exposure: the fifteen years experience of the Brescia area - G. Gregorini, P. Tira, M. Crippa s26

18.00-18.15 22 Assessing occupational exposure to crystalline silica in a population-based study of systemic lupus erythematosus (SLE) - C.G. Parks, G.S. Cooper, L.A. Nylander-French, W.T. Sanderson, J.M. Dement, J.A. Hoppin s26

18.15-18.30 23 Simple and complicated silicosis, silica exposure and occurrence of ANCA positivity - D. Pelclová, Z. Fenclová, J. Bartunková, I. Kolárová, J. Lebedová, M. Hladíková, V. Tesar, D. Dvorák s27

18.30 Closure

October 24, 2002

8.30-9.45 Epidemiologic studies of silicosis and pulmonary impairment - Chairs: D. Goldsmith (USA), A. Marconi (Italy)

8.30-9.00 24 Key note talk: Comparison of risk of silicosis in Chinese tin miners, tungsten miners and pottery workers and South African gold miners: an epidemiological study - E. Hnizdo, J.-Q. Chen, M.D. Attfield, W. Chen, F.J. Hearl, W.E. Wallace s27

9.00-9.15 25 Respiratory impairment in Brazilian foundry workers exposed to sand - E.M.C. Mendonça, R.C.C. Silva, E. Algranti, M.A. Bussacos s28

9.15-9.30 26 Long term exposure to silica in the ceramic industry in Viterbo, Italy: lung function, radiological signs, smoking, and cumulative dose - T. Bellander, F. Cavariani, R. Leonori, A. Quercia, F. Forastiere s28

9.30-9.45 27 Mortality among workers of a plant producing sulfuric acid in Italy with past exposure to silica - A.C. Pesatori, D. Consonni, M. Rubagotti, G. Saporetti, M. Bonzini, P.A. Bertazzi s29

9.45-10.15 Coffee break

10.15-12.45 Cancer epidemiology - Chairs: F. Cavariani (Italy), R.M. Park (USA)

10.15-10.45 28 Key note talk: The methodological and historical development of the epidemiological evidence relating silica exposure and lung cancer - M. Finkelsteine

10.45-11.00 29 Silicosis and lung cancer in Hong Kong, 1981-1999 - T. I. Yu, L. Tse s29

11.00-11.15 30 Mortality from lung cancer among Sardinian silicotic patients (1964-1997) - P. Carta, G. Aru, P. Manca s30

11.15-11.30 31 Coal mine dust exposure, quartz dust exposure, pneumoconiosis development, and lung cancer risk: results from a mortality follow-up study in german coalmining - P. Morfeld, K. Lampert, M. Emmerich, C. Stegmaier, C. Piekarski s30

11.30-11.45 32 Mortality among Italian refractory brick workers exposed to SiO2 - F. Merlo, R. Puntoni, E. Garrone, A. Desideri, M. Ceppi s31

11.45-12.00 33 Mortality in a cohort of miners and quarrymen with exposure to silica dusts - C. Mamo, A. d’Errico, A. Tomaino, M. Demaria, M. Dalmasso, G. Costa s31

12.00-12.15 34 Roles of other workplace carcinogens on the association between silica, silicosis and lung cancer risk - M. Dosemeci, P.L. Cocco, C.H. Rice s32

12.15-12.30 35 Mortality pattern in two cohorts of industrial glass workers with different exposures to silica in Tuscany, Italy - E. Chellini, O. Rossi, L. Turini, C. Di Pede, A.M. Loi, N. Serretti s32

12.30-12.45 36 Talc use and ovarian cancer risk among women in the Central Valley of California - D.F. Goldsmith, H.A. Young, P.K. Mills, D. Riordan s32

13.00-14.00 Lunch

14.00-15.00 Poster viewing

15.00-16.45 Cardiovascular, renal and other diseases - Chairs: P.L. Cocco (Italy), K. Rosenman (USA)

15.00-15.30 37 Key note talk: Comparative risks: the risk of renal disease versus other outcomes due to silica exposure - K. Steenland s33

15.30-15.45 38 Induction of acute phase systemic reactions and ischemic heart disease due to inhalation of fine dust - B. Hilt, J. Holme, T. Qvenild, K. Svendsen s33

15.45-16.00 39 Occupational renal disease A review of 375 autopsy cases with occupational exposures - K. Honma, A. Puapairoj, V. Vallyathan s34

16.00-16.15 40 The role of silica in the pathogenesis of renal vasculitis: epidemiological and in vitro studies - P. Stratta, C. Canavese, A. Messuerotti, A. Campo, B. Bussolati, S. Berutti, A. Grill, L. Sandri, L. Besso, M. Coen, L. Luccoli, G. Piccoli s34

16.15-16.30 41 Ischemic heart disease among miners and other quartz-exposed workers - B. Sjögren, L. Barlow, J. Weiner s34

16.30-16.45 42 Some mechanistic aspects of silica-induced increased predisposition to TB - M. Gulumian, B. Fubini, S. Makhubela s35

16.45-17.00 Coffee break

17.00-18.45 Health Surveillance - Chairs: B. Rosenberg (USA), C. Calabresi (Italy)

17.00-17.30 43 Key note talk: Radiographic imaging in dust exposed workers - What’s New in Old shadows? - J. Parker

17.30-17.45 44 Silica dust exposure associated with an increased risk of TB - G.J. Churchyard, R. Dowdeswell, N. White s35

17.45-18.00 45 Silicosis in Québec (Canada) from 1988 to 1997 - L. De Guire, S. Brisson, S. Provencher s36

18.00-18.15 46 Volcanic ash from the island of Montserrat: some recent toxicological and epidemiological studies - F. Hurley, H. Cowie, D. Cullen, K. Donaldson, B. Miller, A. Jones, A. Searl, C. Soutar, L. Tran s36

18.15-18.30 47 Pneumoconiosis from agricultural dust exposure among California farmworkers - M.B. Schenker, K.E. Pinkerton, B. Elvine-Kreiss, V. Vallyathan, M. Kim, F. Green s36

18.30-18.45 48 Mortality study of a cohort of grey iron foundry workers - K.D. Rosenman, M.J. Reilly, C. Rice, V. Hertzberg s37

18.45-19.30 Poster viewing and Discussion

20.30 Social Dinner

October 25, 2002

8.30-10.45 Experimental research: cellular and in vivo studies - Chairs: R.P.F. Schins (Germany), B. Fubini (Italy)

8.30- 9.00 49 Key note talk: From human and experimental silica pathology to molecular mechanisms: need for studies on transcription factors and signaling pathways in silica carcinogenesis - U. Saffiotti

9.00- 9.15 50 Effects of silica on cultured cells can reflect pathogenic processes of scleroderma-associated fibrosis - U. Anderegg, U.-F. Haustein s37

9.15-9.30 51 Role of the lung fibroblast in the fibrotic processes of silicosis - G. Arcangeli, V. Cupelli, C. Capanni, G. Giuliano s37

9.30- 9.45 52 Phenotypic and numerical chromosome changes during the neoplastic progression of Syrian hamster embryo cells transformed by silica - Z. Elias, O. Poirot, F. Terzetti, M.C. Danière s38

9.45-10.00 53 Influence of the particle size on the carcinogenic effect of quartz dust - A.O.B. Brammertz, N. Ehm, H. Breining, S.B. Schyma, N. Binding, U. Witting s38

10.00-10.15 54 Time course of pulmonary responses to inhalation of crystalline silica in the rat model: evidence for a threshold burden beyond which silicosis progresses without further exposure - V. Castranova, D.W. Porter, P. Willard, A.F. Hubbs, L. Millecchia s39

10.15-10.30 55 In vivo expression of cox-2 in macrophages and epithelial cells after instillation of quartz and surface modified quartz - A. Becker, C. Albrecht, R.P.F. Schins, A. Knaapen, D. Höhr, K. Unfried, P.J.A. Borm s39

10.30-10.45 56 Development of crystallinity, surface reactivity and potential to transform mammalian cells of a heat-treated diatomaceous earth - Z. Elias, I. Fenoglio, O. Poirot, F. Turci, B. Fubini s40

10.45-11.00 Coffee break

11.00-12.00 Experimental research: mechanisms of carcinogenesis - Chairs: F. Merlo (Italy), V. Castranova (USA)

11.00-11.15 57 Apoptosis induction in vitro and in vivo by quartz and kaolin dusts - M. Keane, N. Gao, W. Wallace s40

11.15-11.30 58 Molecular biology study on the carcinogenesis of silica - B. Liu, X. Zhang, P. He, X. Zhang, Q. Miao, B. You, M. Xu, N. Kang, R. Guan, P. Zhou s40

11.30-11.45 59 Activation of protein kinase C is required for silica-induced activation of the MAP kinase-AP-1 pathway - M. Ding, Y. Lu, L. Bowman, C. Huang, V. Castranova s41

11.45-12.00 60 Regulation of silica-induced apoptosis by the tumor suppressor gene, p53 - L. Wang, L. Bowman, Y. Lu, Y. Rojanasakul, R. Mercer, V. Castranova, M. Ding s41

12.00-13.45 Risk assessment, primary prevention and dust control - Chairs: B. Liu (China), S. Silvestri (Italy)

12.00-12.30 61 Key note talk: How risky are current standards for occupational exposure to crystalline silica? - L. Stayner

12.30-12.45 62 Reducing silica exposure to miners at surface operations in the United States - A.B. Cecala, J.A. Organiscak, R.J. Timko, J.F. Colinet, E.D. Thimons, W.A. Heitbrink s42

12.45-13.00 63 Blasting abrasives: health hazard comparison - M. Greskevitch, P. Middendorf, F. Hearl, V. Castranova, H. Ahlers s42

13.00-13.15 64 Occupational exposure to silica in Italy: assessing the extent of workers using administrative data - A. Scarselli, A. Marinaccio, M. Nesti, M. Marconi s43

13.15-13.30 65 Prevention of silicosis in sandblasters. Conduct and outcomes of a program in Québec, Canada - R. Simard, R. Arcand, J. Turcot, P. Pelletier s43

13.30-13.45 66 Reducing exposure to respirable quartz at for drill operators at surface coal mines - J.L. Weeks s44

13.45-14.30 Lunch

14.30-16.00 SILICA RESEARCH AND SCIENCE BASED POLICY - Chairs: A.B. Cecala (USA), F. Carnevale (Italy)

14.30-15.00 67 Key note talk: Health effects of respirable crystalline silica: unanswered questions - F.L. Rice s44

15.00-15.15 68 Lung cancer among silica-exposed workers: is chance the only explanation for contradictory findings? - P.L. Cocco, C. Rice, M. Dosemeci s44

15.15-15.30 69 Crystalline silica: towards regulatory solutions - M. Wyart-Remy s45

15.30-15.45 70 Italian regulation on exposure to crystalline silica - G. Spagnoli, A. Campopiano s45

15.45-16.00 71 Italian law on "Dangerous Chemical Agents" (D.lgs. 25/2002): effects on risk assessment of crystalline silica and on role of Italian National Institute of Insurance against Accidents at Work (INAIL) - P. Altarocca, P. La Pegna, D. Rughi, U. Verdel s46

16.00-17.00 Conclusions and perspectives

73 Key note talk: Research issues and prevention policy: what have we learned from ISSSCOD3? - F. Merlo, A. Balletta, D.F. Goldsmith

17.00 Closure of the conference

Poster SESSIONS

1. Industrial hygiene and ambient sampling methods - Chairs: F. Cavariani (Italy), C. Rice (USA)

309 . Mapping of quartz distribution in Campania’s (Italy) calcareous-dolomitica succession - M. Casale, R. D’Angelo, P. De Blasi, P. Desideri, C. Novi, S. Sinopoli s53
310 . Quartz concentration and morphological characteristics in volcanic series: relationship with genesis mechanisms in Campi Flegrei (Campania, Italy) formations - M. Casale s53
316 . Pollution of quartz dust during mining and manufacturing of porphyry in Trentino: a statistical analysis of exposure results in the years 1995-2001. - C. Buffa, C. Correzzola, A. Piccioni, G. Pol s55
317 . The mining activity of sand-quarries: hygienistic and occupational aspects - S. Barca, P. De Santis, R. Nitti, G. Rosci s56
319 . Silica presence in building materials in Italy: preliminary results - G. Castellet y Ballarà, F. Cavariani, M. De Rossi, P. De Simone, C. Fanizza, F. Fioravanti, A. Marconi, F. Paglietti, D. Ramires, G. Spagnoli s56
320 . Characterisation of alumino-silicate ceramic fibres devetrification during high temperature working conditions - P. Comodi, P. Garofani, G.D. Gatta, P.F. Zanazzi, R. Vivani, G. Miscetti s57
329 . The determination of quartz by ft-ir spectrophotometry using fourth derivative spectra - A. Maciejewska, I. Szadkowska-Stanczyk s60
337 . Critical review on silica exposure during foundry activities in Lombard Region - F. Pisanelli, B. Rimoldi, P. Santucciu, L. Tripi s63
338 . Occupational exposure to crystalline silica dust in sanitary ware industry - A. Campopiano, S. Casciardi, D. Lega, F. Fioravanti, D. Ramires, G. Spagnoli s64
339 . Identification of quartz and other minerals in cigarettes - W.E. Stephens, A. Calder, D.A. Herd, J.A.Wickenden s64
347 . Classroom chalk: a possible new source of exposure to crystalline silica - J.B. Westin, E. Bitchatchi, E.D. Richter s67

2. Experimental research: role of physicochemical features, cellular and in vivo studies and mechanism of carcinogenesis - Chairs: B. Fubini (Italy), R.P.F. Schins (Germany)456 Work and women’s health (Abstracts 097-098)

301 . Importance of surface characteristics of quartz dq12 for acute and chronic inflammation in the rat lung - C. Albrecht, A. Becker, R.P.F. Schins, D. Höhr, K. Unfried, A. Knaapen, P.J.A. Borm s49
303 . Uptake of silica DQ12 by fibroblasts and endothelial cells in vitro - U. Anderegg, G. Fitzl, J. Krosche, U.-F. Haustein s50
306 . In vivo expression of COX-2 in macrophages and epithelial cells after instillation of quartz and surface modified quartz - A. Becker, C. Albrecht, R.P.F. Schins, A. Knaapen, D. Höhr, K. Unfried, P.J.A. Borm s51
313 . Interaction between ascorbic acid and various silica polymorphs: role of the surface structure of silicas - R. Ceschino, G. Martra, I. Fenoglio, M. Tomatis, B. Fubini s54
315 . Devitrification products of aluminosilicate refractory fibers after use as high-temperature furnace insulant: studies by xrd, ftir, optical and electronic microscopy, and exposure data - M. Casale, G. Castellet y Ballarà, R. Continisio, E. Della Penda, G. Gargaro, L. Mercadante, A. Marconi, S. Massera, C. Novi, F. Ruspolini, S. Sinopoli s55
321 . A pre-treatment in ascorbic acid increases quartz toxicity to a murine macrophage cell line - M. Giovine, I. Fenoglio, M. Pozzolini, S. Scarfì, B. Fubini, U. Benatti s57
324 . Determination of oxidative, inflammatory and genotoxic response by silica and coal mine dust using an in vitro two-phase model with human whole blood - W. Hadnagy, H. Idel s59
327 . Surface reactivity of crystalline-silica-rich volcanic ash, with implications for health hazards - C.J. Horwell, I. Fenoglio, R.S.J. Sparks, V. Ragnarsdottir, B. Fubini s60
328 . Hazardous effect of TAFMAG, a substitute of asbestos, in Korea - Y. Lim, K.A. Kim, K.H. Lee s60
331 . Inflammatory effects of quartz samples after intratracheal instillation in rats - O. Creutzenberg, G. Oberdörster, S.G. Ampian, W.F. Moll, R. Hamilton, H. Muhle s61
353 . Inflammatory effects of quartz samples after intratrachael installation in rats: mineral characterization - S.G. Ampian, W.F. Moll s69

3. Epidemiologic studies of silicosis and pulmonary impairment - Chairs: T. Bellander (Italy), M. Gulumian (South Africa)

300 . The silicosis risk in the Veneto Region - R. Addia, D. Candido, R. Compagnoni, L.A. Magrì, G.B. Perrone s49
305 . Respiratory disorders in lignite mine workers - R.C. Artenie, N. Simionescu, C. Dumitru, F. Stroe s51
311 . Silicosis risk in ceramic products: crystalline silica from raw material to products. - M. Casale, R. Buzzi, U. Verdel s53
322 . Silicosis and cancer: the experience of the National Institute of Insurance Against Accidents at Work (INAIL) - S. Greco, N. Lagattolla, M. Martini, M.A. Orgolesu s57
325 . Silicosis, mixed dust pneumoconiosis and lung cancer: 2nd autopsy report with a reference to its precursor lesions - K. Honma s59
326 . Pulmonary alveolar proteinosis and pneumoconiosis - K. Honma s59
330 . Particulate exposure during the Gulf War; with an emphasis on silica exposure - R.D. Thomas, J.F. Meagher, C. McMullin, T.J. Vigerstad s61
342 . Silicosis in Romania: Who? When? Why? What must be done? Aspects of incidence in the past and present (1992-2002) - A. Todea, A. Ferencz s65
343 . Silicotics in Germany - mortality risk and exposure level - K. Ulm, H. Ehnes, K. Guldner, D. Kieser s66
345 . Mechanisms of crystalline silica and coal-induced emphysema development - V. Vallyathan, E. Hnizdo s66
348 . About one case of acute silicosis: a current risk in the rubber industry - P.G. Barbieri, R. Calisti s67
349 . Analysis of occupational lung disease identified at autopsy in the South African mining industry - J. Murray, P. Back s68

4. Cancer epidemiology, cardiovascular, renal, autoimmune and other diseases - Chairs: B. Hilth (Norway), E. Chellini (Italy)

314 . Occupational risk of rheumatoid arthritis - P. Nurchis, M.R. Milia, A. Piria, P.L. Cocco s55
323 . Autoantibodies and altered renal indices in a large group of silica exposed patients - G. Gregorini, M. Crippa, P. Tira, J. Frizza, R. Maiorca s58
332 . Silicosis and lung cancer in (East) German uranium mining - H. Otten, F. Lehmann, D. Koppisch, O. Hagemeyer s62
340 . Silica-containing dust exposure, risk of lung cancer and attributable fraction for the population based on the nested case-control analysis within a cohort of pulp and paper workers - I. Szadkowska-Stanczyk, W. Symczak, W. Sobala s65
350 . Lung cancer in Vermont granite workers-an update - W.G.B. Graham, P.M. Vaceck, J. Costello s68
351 . Mortality in a cohort of workers exposed to porphyry dust in Trento province. Preliminary results - A. Cristofolini, S. Piffer, E. Mon, R. Micciolo, L. Canal s69

5. Risk assessment, primary prevention and dust control, health surveillance, silica research and science policy - Chairs: J. Parker (USA), P. Altarocca (Italy)

302 . Proposal of technical guidelines concerning risk assessment of crystalline silica dust - P. Altarocca, P. La Pegna, D. Rughi, U. Verdel s50
304 . Silicosis risk in the ceramic production in Latium, Italy: INAIL management of the silicosis additional insurance charge - B.M. Antonelli, T. Aureli, P. Desideri, E. Incocciati, E. Marchesi s50
307 . Results of screening of a group of sanitary ware workers - L. Boschero, G. Ciprietti, R. Ferri, G. Pizzutelli, G. Spagnoli s52
308 . "Souvenir" silicosis - R.S. Carel s52
312 . Esposti: a tool for managing health and environment in a silica dust exposed population - F. Cavariani, L. Bedini, G.Manzari, E. Valenti, I. Scrocchia, S. Franco, A. Quercia s54
318 . Study on interactions between silica and some drugs used to prevent silicosis - R.S. Dumitru, C. Mandravel s56
333 . Risk assessment of silica containing dusts in workplaces: experimental comparison between two different methods - F. Cavariani, P. De Blasi, M. De Rossi, E. Incocciati, P. La Pegna, S. Massera, R. Piccioni, D. Rughi s62
334 . National and international reviews of crystalline silica - F.L. Rice s62
335 . The Italian experience on silica exposure and its health effects: the Italian Silica Initiative (ISI) - C. Calabresi, F. Forastiere, F. Merlo, A. Marconi, M. Nesti, U. Verdel, S. Silvestri, F. Cavariani, A. Quercia (on the behalf of the Italian Silica Initiative) s63
354 . Silicosis risk assessment in Val Fontanabuona, Italy, slate district - P. Clerici, C. Guidi, M. Mattarelli, R. Gallanelli, D. Magnante, G. La Manna, D. Sarto, C. Zecchi s69
355 . Silicosis among gold miners in Ecuador: a present problem - R. Harari, D. Herrera, J.E. Parker s70
336 . Prevention and control of silicosis in India - H.N. Saiyed, H.G. Sadhu, Y.K. Sharma, D.J. Parikh, L.J. Bhagia, R.N. Tiwari, K. Rajnarayan s63
346 . Positron Emission Tomographic (PET) imaging of silicosis in a rabbit model using an 18F-Fluorinated proline amino acid analog tracer - W.E. Wallace, N.C. Gupta, A.F. Hubbs, S.M. Mazza, H.A. Bishop, M.J. Keane, L.A. Battelli, J.Y.C. Ma, P. Schleiff s66

Volume 93, n. 6

Novembre-Dicembre 2002

APPUNTI DI METODO

NOTES ON THE METHODS

491.

La Direttiva europea 2002/44/CE sulla protezione dei lavoratori contro i rischi da vibrazioni meccaniche The European Directive 2002/44/CE on the protection of workers against risks arising from mechanical vibration - M. Bovenzi

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ARTICOLI SPECIALI

SPECIAL ARTICLES

499.	SV40: un possibile co-cancerogeno dell’amianto nella patogenesi del mesotelioma? SV40: a possible co-carcinogen of asbestos in the pathogenesis of mesothelioma? - A. Cristaudo, R. Foddis, L. Bigdeli, A. Vivaldi, R. Buselli, G. Guglielmi, M. Guidi, F. Ottenga
507.	La valutazione dell’esposizione ad amianto in Toscana attraverso i dati dell’Archivio Regionale Toscano dei Mesoteliomi Maligni (1988-2000) Tuscany Mesothelioma Registry (1988-2000): evaluation of asbestos exposure - G. Gorini, S. Silvestri, E. Merler, E. Chellini, V. Cacciarini, A. Seniori Costantini

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ARTICOLI ORIGINALI

ORIGINAL ARTICLES

519.	Mortality of a cohort of road construction and maintenance workers with work disability compensation Mortalità di una coorte di lavoratori del settore "costruzione e manutenzione strade" con rendita per invalidità lavorativa - A. d’Errico, C. Mamo, A. Tomaino, M. Dalmasso, M. Demaria, G. Costa
527.	Contaminazione da radon indoor nelle abitazioni pugliesi e valutazione della probabilità di insorgenza di tumore polmonare nella popolazione residente Contamination by indoor radon in houses in the Apulian Region of Italy and evaluation of the probability of lung cancer in the population - N. L’Abbate, P. Marcuccio, C. Dipace, M. Carbonara, E. Carioggia, V. Martucci, S. Salamanna, G. Simeone, L. Vitucci
540.	Strenuous exercise and action of antioxidant enzymes Esercizio fisico pesante e attività di enzimi antiossidanti - D. Vesovic, S. Borjanovic, S. Markovic, A. Vidakovic

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LETTERE IN REDAZIONE

LETTERS TO THE EDITOR

561. Ancora sulla celebrazione del Centenario della "Clinica del Lavoro" di Milano - (K.E. White)

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562 NECROLOGIO

OBITUARY

Commemorazione del Prof. Paolo Chiesura Corona (B. Saia)

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563 NOTIZIARIO

NEWS

Il futuro della Medicina del Lavoro in Europa. Rapporto della Conferenza dell’Unione Europea dei Medici Specialisti (Sezione di Medicina del Lavoro) tenutasi a Barcellona il 13 e 14 settembre 2002 (G. Franco)
Congresso Internazionale Donne Lavoro e Salute. Stoccolma, 2-5 giugno 2002 (S. Salerno, N. Barbini, D. Fano, M. Finardi)